Not only does generative AI spark revolutionary changes with applications growingly spanning across all industries, but it has also become the first solution that companies choose to build up their competitiveness.Startups that drive global business transformation are increasingly utilizing generative AI to develop new products or services as a way to grab the attention of angel investors and enterprise users. To allow more enterprises to see what Taiwan-based startups have accomplished with generative AI, DIGITIMES and Taiwan Tech Arena (TTA), a flagship startup program funded by the National Science and Technology Council (NSTC), held Enterprise Connect - Generative AI Startup Pitch Day on July 23, 2024, with technical support from Amazon Web Services (AWS).The event gathered promising startups to present their generative AI solutions and attracted a great number of corporate venture capital and new business development specialists who hoped to connect with the startups through the one-to-one matchmaking activity and thereby build a solid foundation for their companies' long-term development.According to Yi-Bin Chen, Director, Integrated Marketing Department, DIGITIMES, startups are playing a growingly important role in the global marketplace. Because of this, CES has an exhibition area specially designed for startups to demonstrate their promising potential. TTA led 96 startup teams to participate at CES 2024 and organized the TTA Taiwan Pavilion, where the teams showcased their innovations and successfully grabbed the attention of venture capitalists from all over the world.Today everyone is talking about AI. AWS is among the few cloud computing pioneers that are capable of providing total AI solutions. AWS has been supporting and helping startups achieve great achievements over the long run.Andrea Hsu, Director General, Department of Academia-Industry Collaboration and Science Park Affairs, National Science and Technology Council (NSTC), noted that by establishing TTA in 2018, NSTC aims to bridge Taiwan-based startups with the international community to thereby drive innovations and developments across many industries. As of today, TTA works with close to ten accelerators to bring resources and technologies to support startups' early-stage development.More than 900 startup teams have flourished thanks to TTA. Today, AI has become the engine that drives digital transformation for global industries. At CES 2024, AWS invited the teams for a visit to the Amazon fulfillment center to witness how AI was used to process shipments. That was very inspiring to the teams that use generative AI to develop innovative services. It is hoped that bridging startups with enterprises will build positive momentum for Taiwan's industry upgrade.Chester Hsieh, Head of Taiwan Sales, Head of Strategic Programs, Hong Kong and Taiwan, AWS, commented that AWS has been working with startups for years. AWS is adopted by more than 80% of the unicorns in the world including Netflix, Airbnb, and Uber as well as Taiwan-based KKBOX and 91APP. Among those that endeavor in AI, 96% have chosen AWS. Since 2000, Amazon has been utilizing AI technologies.AWS offers a wide range of high-performing foundation models (FM) from leading AI companies for startups to choose from based on their products and services. AWS was pleased to support TTA and DIGITIMES in holding the event connecting startups with enterprises.Moreover, in recent years, Amazon has been actively utilizing generative AI to enable new services. For example, it is used to collect and sort customer comments at Amazon's online bookstore to help consumers make purchase decisions. Furthermore, generative AI is also used for Alexa, the voice assistant that many people are familiar with, and for shipment schedule prediction and package arrival notices for orders placed on Amazon Pharmacy. All of the aforementioned innovative services rely on the robust computing power and advanced machine learning technologies provided by AWS.Eye-catching generative AI solutions from startupsNine startup teams supported by TTA and AWS Joint Innovation Center (JIC) participated in Enterprise Connect - Generative AI Startup Pitch Day. Based on their products or services, they were divided into different categories including audio tech, RPA software, energy, no-code AI, cyber security, martech, and law tech.In the cyber security category, Cymetrics, a subsidiary of OneDegree Global, provides a complete range of cyber security assessment and inspection products and services. For example, its LLM-based cyber security inspection service helps users improve the visibility of vulnerabilities and manage risks with more agility and flexibility.Authme is an authentication solution built on AI and machine learning to enable security, convenience, and regulatory compliance for corporations. Authme has developed authentication, face recognition, and biometric liveness detection systems that safeguard against identity frauds and Deepfake attacks while reducing inspection costs and enhancing user experience.Amid the rising popularity of robotic process automation (RPA) software, IsCoolLab with years of experience in professional software development introduced Robotiive. The patented AI-enabled solution integrates and modularizes a variety of automation capabilities to allow users with no coding experience to easily automate their process in any use scenario.In support of energy efficiency initiatives, PurismEV developed a proprietary AI-based solution that increases EV range by 40% and extends battery life 2.3 times to address EV owners' range anxiety. The solution is being used in delivery trucks, ride-sharing electric motorcycles, off-road electric bikes, and race cars.With user experience being a top priority, DeepWave, in the audio tech category, is committed to AI-enabled voice recognition solution development and application. It provides customers with an all-in-one digital audio processing solution for voiceprint recognition, active noise reduction, noise cancellation, and voiceprint comparison.Its solution has been used in smart manufacturing, digital content processing, music entertainment, and education. In the law tech category, Legal Tech, founded by a group of lawyers, presented a one-stop contract lifecycle management solution, LegalSign.ai, based on generative AI. Encompassing contract lifecycle management, electronic signing, and AI legal assistant, the solution improves efficiency and minimizes risks for corporate legal teams, allowing them to deliver greater business value.To help circumvent the current AI talent shortage, many companies have developed no-code AI solutions to lower the barrier to AI adoption. Chimes AI introduced Tukey, a solution that allows factory workers to extract data and build AI models using the automatic model packaging function and connect with enterprise information services in a snap.Tricuss presented an enterprise-level LLM-based solution to improve efficiency for operations such as document integration, automated sorting, and data entry as well as knowledge management and consolidation. Featuring a simple user interface and guaranteed accuracy, the solution boosts productivity for all kinds of corporate functions.BigGo, a star that shines brilliantly in the martech sector, operates the biggest e-commerce product search and price comparison website in Southeast Asia and Taiwan. It debuted two new AI tools in 2024. One is BIRSE, an image search engine that searches for products based on images. The other is the BigGo Description Generator, which generates accurate product descriptions using AI.The final section of the event was a one-to-one matchmaking activity aimed at connecting startups with prospective partners who can help them with fundraising, market expansion, and technology development. The activity marked a perfect ending to the Enterprise Connect - Generative AI Startup Pitch Day.DIGITIMES, TTA, and AWS representatives at Enterprise Connect - Generative AI Startup Pitch Day. Credit: DIGITIMES

Targeting one of the most complex and sensitive parts of the human body, any minor error during a spinal surgery could lead to severe consequences such as infection, nerve damage, or spinal cord injury. This makes spinal surgery a high-risk surgical procedure.To overcome the challenges, Point Robotics MedTech created a minimally invasive spine surgery robot platform by combining medical expertise and state-of-the-art technologies such as robotic arms, optical positioning, and algorithms. The platform can help surgeons perform complex spinal surgeries with high precision and optimize the patient's medical experience.Point Robotics' surgical robotics technology is inherited from a professor at Imperial College London with over 30 years of experience. The company was founded in 2016 with support from the National Science Council's Germination Program. It aims to leverage the technical prowess of Taiwan's medical and mechanical industries to develop a spinal surgery robot that assists surgeons in enhancing surgical precision and reducing risks.Minimally Invasive Spine Surgical Robot with Precision and ReliabilityAccording to Brad Lin, Chief Marketing Officer of Point Robotics, there are two main challenges in existing spine surgeries. First, surgical precision requirements from medical institutions and patients are increasing, especially in minimally invasive surgeries.Traditional surgeries rely on surgeons' experience and tactile sensation, but this approach has limitations, particularly in tasks like bone grinding, where achieving high precision is more challenging. Moreover, surgeons performing spine surgeries over a long period are prone to wrist and eye fatigue, which can adversely affect surgical quality and career longevity.The second challenge lies in the increasing expectations of patients regarding surgical outcomes and post-operative recovery periods. Improving surgical efficiency and post-operative recovery outcomes have become significant missions for medical institutions. Not only to achieve precision, surgeries today also aim to minimize incisions and recovery time as much as possible.While technologies and equipment for spinal surgery have advanced rapidly, there is still room for improvement to meet all those demands. Particularly in the realm of robotic surgery equipment, existing systems are mostly focused on soft tissue surgeries, with fewer applications for hard tissue surgeries. Point Robotics' minimally invasive spine surgery robot and navigation system are perfect for addressing clinical needs today.Michael Lo, Head of Corporate Strategy of Point Robotics, explained the architecture of their product, which integrates a six-motored robotic end-effector with navigation systems and control technology, combining precision and flexibility. The company's surgical robot uses a robotic end-effector to compensate for deviations from the planned path, enabling real-time tracking of patient movement during surgery. This allows surgeons to perform precise and stable surgeries.By precisely controlling the robotic end-effector, the surgical robot has expanded its functionality to decompression capabilities. The precision of bone grinding can reach mere paper-thin thickness. During surgery, the force feedback system detects changes in bone density and dynamically adjusts grinding force, depth, and path accordingly to ensure surgical precision and safety.Point Robotics' Detail-focused Product Development Builds a ReputationAccording to Lo, for a medical device to gain industry recognition and successfully commercialize, it needs to overcome technical challenges and undergo lengthy clinical validation. "Robotic technologies are categorized as the high-precision, cutting-edge field, and the medical products are closely related to human safety," he emphasized. Thus, every prototype of a medical device must undergo rigorous validation and continuous communication with clinical physicians to ensure that the product design meets medical needs.In practical application, variations in each patient's bone density and other external factors can also impact the surgery process and outcomes, presenting challenges from theory to clinical practice and commercialization. Point Robotics' products have undergone iterative modifications and validation to achieve the clinical benefits doctors expect.Point Robotics' navigation system has been in clinical use since 2023. As of now, it has been utilized in 150 surgeries. The first-generation navigation system and robotic-assisted surgical system were cleared by the U.S. FDA and certificated by Taiwan FDA between 2022 and 2023.Regarding the product marketing plan, Lo mentioned that because the medical industry is typically cautious about new products, they will initially focus on the navigation system, which has higher market acceptance. Next, the company will develop a decompression surgery robot capable of performing various functions such as bone grinding, assisting surgeons in conducting more spine surgeries and improving surgical efficiency.According to Lo and Lin, the success of Point Robotics' technology in transferring from concept to product is due not only to the full commitment of the team members but also to the continuously improving ecosystem for startups in Taiwan. For example, while Point Robotics was looking for clinical resources, BE Accelerator – a TTA accelerator partner, helped the company connect with suitable physicians, enabled product testing, and received feedback on suggestions and feasible directions.The locally enthusiastic startup atmosphere and policy support have also attracted many young overseas Taiwanese entrepreneurs to return home. These entrepreneurs bring back global perspectives and innovative thinking. When combined with Taiwan's technology, medical and manufacturing industries, a virtuous cycle begins.Looking ahead, Taiwan's startup ecosystem is expected to mature further and be more internationalized. Point Robotics also looks forward to interacting and collaborating with other companies, expanding Taiwan's influence in the global medical technology field.(Editor's note: The original article was published in TTA Magazine Issue 14. Read more startup stories in TTA Magazines.)Point Robotics’ robotic-assisted surgical system and navigation system can help surgeons perform complex minimally invasive surgeries with high precision.

Cerebrovascular Accidents (CVAs), or stroke, are the top cause of disability and the second leading cause of death worldwide, posing significant threats to human health.Unfortunately, many individuals only become aware of their condition after experiencing a stroke, missing the optimal window for early intervention and treatment.Carotid Artery Stenosis (CAS) has been identified as a crucial factor contributing to strokes, serving as an early indicator. Therefore, early detection and treatment of carotid artery stenosis are vital measures for stroke prevention.However, traditional methods for detecting carotid artery stenosis are limited by expensive equipment, heavy reliance on specialized medical personnel for operation and interpretation, lengthy testing procedures, and high costs, preventing widespread early detection of risk for stroke.Through collaboration with a team of professionals from National Taiwan University, Pulxion Medical Technology has developed a non-invasive AI imaging technology for rapid screening of the risk of carotid artery stenosis, PulStroke, which breaks through traditional testing limitations.With rapidity, standardization, and high cost-effectiveness features, the technology can significantly reduce the need for medical manpower and resources. It is poised to enhance the accessibility of early stroke screening greatly.The limitations of traditional methods make early stroke detection challengingPulxion was founded by Professor Hao-Ming Hsiao from the Department of Mechanical Engineering at National Taiwan University. The co-founder is Dr. Hsien-Li Kao, a Professor in the Medicine School at the National Taiwan University and Chairman of the Cardiology Division at the National Taiwan University Hospital. Their long-term collaboration started in 2014, dedicated to addressing numerous challenges in early stroke detection, and they officially established Pulxion in 2020.According to Professor Hsiao, the main reason for choosing the carotid artery as the topic of their research is that there are over 12 million new cases of stroke worldwide every year, which means one new case occurs every 3 seconds. It is not only a threat to human health but also significantly impacts healthcare and societal costs. There's an estimation that by 2030, the global economic burden of stroke, including post-care, will exceed one trillion US dollars.Carotid artery stenosis serves as a critical early indicator of stroke. Existing common diagnostic methods for carotid artery stenosis include carotid artery ultrasound, Computed Tomography Angiography (CTA), and Magnetic Resonance Angiography (MRA). However, due to issues such as expensive equipment and complex operations, early screening is challenging to implement widely.The carotid artery is the closest blood vessel to the body's surface, making it easier to observe the pulsation characteristics. Therefore, Pulxion starts with carotid artery stenosis assessment and utilizes non-invasive AI imaging technology to evaluate the risk of stroke.Unique Screening Method: Rapid, Accurate, and Easy-to-UseBy analyzing subtle pulsation variations on the subject's skin surface, Pulxion's PulStroke can differentiate between the pulsation patterns of normal individuals and those with carotid artery stenosis. The device projects visible light onto the subject's neck and then performs the video motion analysis with AI algorithms to highlight skin surface pulsations.Comparing these pulsations with features associated with carotid artery stenosis, a risk assessment report is generated to evaluate the subject's risk of carotid artery stenosis. The entire process is completed within 1 minute, with reports available within 5 minutes.PulStroke possesses several key advantages. First, compared to traditional methods like carotid artery ultrasound, CTA, and MRA, the technology is non-invasive, offering a non-invasive and radiation-free screening approach for subjects.Second, it's portable and user-friendly, with a compact size and no need for specialized operators, making it suitable for placement in small to medium-sized clinics, health examination centers, and potentially homecare and community service in the future. Third, utilizing AI algorithms and big data analysis supported by PulStroke, clinical trials have demonstrated an accuracy of nearly 90% when compared to ultrasound.Regarding the business model, Joy Chen, CEO of Pulxion, said that PulStroke includes both hardware device and cloud platform. The hardware device can be set up in medical facilities with buyout or leasing options. The analysis reports generated on the cloud platform are billed separately and also come with several options for users.For marketing, Pulxion will first work with health examination centers and large hospitals, with plans to participate in government disease prevention programs. The next step is to enter the community clinics with the ultimate vision of making the technology accessible to the general public and integrating it into home healthcare and nationwide health services to increase stroke screening rates and ultimately reduce stroke incidence.Pulxion has completed its angel round funding and plans to sign an MOU with internationally renowned medical device companies this year. Pulxion also plans to file the medical device regulatory submission to the Taiwan Food and Drug Administration (TFDA) this year and is preparing to apply for the Breakthrough Devices Program of the U.S. Food and Drug Administration (FDA).Chen said that Taiwan will be the first launch market for Pulxion, and the company will subsequently begin preparations for regulatory submission in the United States.PulStroke enables rapid and accurate assessment of stroke risk. The company immediately attracted attention from the medical industry upon its release. Professor Hsiao believes the key driving force behind the successful commercialization of Pulxion technology is the Startup Value Creation Program promoted by the National Science and Technology Council. As he mentioned, the program activates the value of academic research by providing resources, regulatory ease, and policy support to allow professors to play significant roles in startups. It also encourages various forms of innovation matchmaking.Pulxion has participated in the acceleration program of Mosaic Venture Lab – a TTA accelerator partner as well. The program not only organizes various activities to increase interaction opportunities with investors but also helps startups to expand their exposure. All the support for Pulxion has transformed into its competitiveness. The company will do its best to broaden the applications of its technology to other diseases, creating a healthy society in the future and fulfilling its vision of preventive medicine and home healthcare.(Editor's note: The original article was published in TTA Magazine Issue 14. Read more startup stories in TTA Magazines.)Pulxion PulStrokePhoto: Pulxion

Endoscopes play an instrumental role in minimally invasive surgeries.They allow doctors to perform inspection and treatment procedures inside the body using smaller surgical cuts or even without cuts while increasing surgical precision. EndoSemio's single-use endoscope developed on the foundation of miniature imaging devices and high biocompatibility tubing materials boosts surgical safety, drives technological innovations, and satisfies special healthcare needs. With EndoSemio's single-use endoscope, hospitals will be able to improve patient experience.Leveraging technological and medical strengths, EndoSemio overcomes the shortcomings of traditional endoscopesTing-Xuan Chen and Chih-Peng Lin co-founded EndoSemio. Chen worked for the Industrial Technology Research Institute (ITRI) in charge of helping medical research organizations turn clinical needs into products.Lin is an attending physician and director of the Division of Pain Management, Department of Anesthesiology, National Taiwan University Hospital. Their decade-long partnership has brought multiple healthcare products into reality.Following his return to Taiwan after completing advanced study at Stanford University, Lin found Taiwan's healthcare sector, despite being among the world's front runners, still has needs that were not addressed due to the lack of cross-industry collaborations. Such needs can be fulfilled through rapid prototyping and technological R&D to thereby improve healthcare quality and efficiency. This prompted Chen and Lin to establish EndoSemio, focusing on special-purpose single-use endoscopes to solve the many pain points of traditional endoscopes and address a small portion of clinical needs. According to Chen, an endoscope reprocessing guide easily goes over 100 pages and contains more than 150 procedures. In reality, as high as 45% of the important cleaning steps are skipped as they are too complicated.In particular, the steps of brushing the accessible channels and forced air drying are often carried out for no longer than 50% of the specified duration. Furthermore, not only is it costly and labor-intensive to maintain traditional endoscopes, but improper cleaning may also lead to cross infections. All the time and effort for disinfection and preparation also hinder patient flow and undermine hospital operation efficiency. The slew of limitations with traditional endoscopes give rise to tremendous opportunities for single-use endoscopes. FDA has approved multiple single-use endoscopes in recent years as part of the efforts to promote such products.As opposed to traditional endoscopes with a long history, single-use endoscopes are still in early-stage development. Those currently available on the market generally target large usage applications, rather than special-purpose small-quantity needs. In view of this, EndoSemio decided to start with tracheostomy endoscopes, neonatal catheters, and flexible ureteroscopes.EndoSemio introduces three single-use endoscope products to meet clinical needs According to Lin, a traditional tracheostomy requires two teams of medical professionals, one monitoring the bronchoscopy while the other performing the tracheostomy. Things could go wrong when surgeons have to perform tracheostomy without bronchoscopic images.Without an imaging system on the tracheal tube, surgeons can only rely on experiences and feel the way through. Now with EndoSemio's innovative endoscope imaging tracheostomy kit, featuring the world's first tracheal tubes integrated with endoscopes, medical professionals can avoid complications and mitigate the risk of incorrect placement in false lumen, improving tracheostomy efficiency and ensuring patient safety.The product has won the 20th National Innovation Award. Neonatal respiratory imaging devices are generally miniaturized.Their level of precision is critical to neonatal respiratory care. EndoSemio's neonatal and pediatric respiratory imaging catheters help physicians correctly identify delicate infant airways and examine the conditions therein to effectively lower the risks of hypoxia or complications.The flexible ureteroscopes that EndoSemio provides combine miniature imaging modules with tubes made of advanced materials to enable visibility. The solution reduces chances of infection and cross-infection and therefore is an ideal choice for stone removal in a laser lithotripsy.Lin pointed out EndoSemio's advantages in a few aspects. First, the EndoSemio team interviewed 20-some physicians and designed the products based on their comments and feedback to ensure the products addressed their needs. As such, the resulting products feature a user-friendly interface and simple structure design, requiring no learning curve for users to effortlessly operate. Moreover, their digital imaging and navigation functions with enhanced navigation precision and optimized operation flow are also highly praised by medical professionals.Second, the EndoSemio engineering team has a decade-long experience developing endoscopes. Integrated with patented designs including medical-grade high-resolution miniature CMOS image sensors, color calibration, and silicon endoscope tubing, EndoSemio's products boast superior performance and reliability. Last but not least, EndoSemio has grasped critical manufacturing know-how for miniature front-end camera modules and tubing so it has full control over its product quality and performance. It is also able to keep costs at bay through vertical integration efforts.EndoSemio has submitted applications for FDA approval. It expects to obtain FDA approval by year-end 2024, allowing it to launch the products in 2025. Everything is proceeding according to schedule, noted Chen.For the smooth progress, EndoSemio gives credit to not only team efforts but also Taiwan's startup environment fostered by industry-government-academia-research collaborations. Lin spoke candidly that physicians or scholars involved in startup ventures were considered impractical but things are different today.Taiwan's startup scene, especially in the healthcare sector, has exhibited significant changes in the recent decade. The National Science and Technology Council and the Ministry of Economic Affairs support multiple projects aimed at cultivating an environment that appeals to entrepreneurs and effectively accelerates startup development. Going forward, EndoSemio has set goals for each development stage and will continue to endeavor on medical imaging solutions for special-purpose applications to help medical institutions create premium patient experiences.(Editor's note: The original article was published in TTA Magazine Issue 14. Read more startup stories in TTA Magazines.)Innovative endoscope imaging tracheostomy kitPhoto: EndoSemioNeonatal and pediatric respiratory imaging cathetersPhoto: EndoSemioEndoSemio's neonatal and pediatric respiratory imaging catheters on display at a medical technology exhibitionPhoto: EndoSemio

Consumers' growing favor for stylish clothing has given rise to a rapid increase in fast fashion brands over the recent decade.However, low-quality fast fashion apparel has also made consumers demand more from fashion brands. Especially in developed countries where birth rates are declining, parents are inclined to spend more on the clothes they put on their children to ensure comfort and safety. According to market research reports, the global organic cotton children's apparel market is set to grow at a CAGR of 9.4% from US$4.4 billion in 2022 to US$8.8 billion in 2030. For their outstanding quality, Taiwan-based fashion startup Baby Baby Cool's products are carried in French department store Printemps.It is the only local brand available at the Bellavita Shopping Center in Taiwan. Better yet, it has signed agreements with Japan's Hankyu Department Store and Isetan Department Store to sell Baby Baby CoolBaby Baby CoolBaby Baby CoolBaby Baby CoolBaby Baby CoolBaby Baby Cool apparel in their stores starting in the second quarter of 2024.Erin Wei, founder and director of Baby Baby Cool, remarked that she established the company to help children develop a sense of taste and style at a young age by providing chic fashion for children as opposed to common kids' wear with cartoon illustrations on the market. When selecting fabrics with manufacturers, she found most of them are produced using chemicals in the process which children may absorb through their skin, harming their health and the environment. To protect the health of infants and kids, Wei decided to use organic cotton to make safe and stylish fashion for children.Premium organic cotton combined with fashion design and craftsmanshipFounded in 2016 on the core concept of love and aesthetics, Baby Baby Cool aims to foster children's sense of taste and style through fashion design while safeguarding their health starting with the clothes they wear every day. The company insists on using GOTS-certified premium organic cotton and proven non-toxic metal accessories to produce pure, soft, and comfortable clothes that kids can confidently put on.Applying the techniques and craftsmanship used for adult fashion to design children's wear, the Baby Baby Cool team goes beyond the boundaries of kids' apparel and creates a Taiwan-based fashion brand boasting both style and health. Featuring originality, the Baby Baby Cool team comprises professional advertisement stylists, prominent fashion designers, skilled pattern makers, and experienced seamstresses who work together to produce clothing entirely in-house.Making use of proportions, structures, cuttings, simple yet vivid colors, and patching techniques to create interesting and innovative aesthetics, the team makes children's clothing featuring sleek lines, chic style, and simple colors. Their products with the unique style allow the world to see Taiwan's strength in children's clothing design.Wei noted that there are kids' fashion brands on the market that highlight the use of organic cotton but they often lack design elements that appeal to consumers. Despite being a startup company, Baby Baby Cool uses special 3D tailoring generally used only for luxury fashion to deliver a more three-dimensional look through cutting, folding, shrinking, grabbing, and pinning techniques.3D tailoring is a technique that leading international fashion brands have growingly adopted in recent years. Although everything about 3D tailoring is more costly and challenging from design to manufacturing compared to conventional practices, it can make clothes that better fit the body contour and structure. This is why Baby Baby Cool is enthusiastically embraced by the market.Leveraging TTA's diverse services, Baby Baby Cool forays into worldwide markets Adhering to the principles of making healthy and stylish clothing, in 2017, a Baby Baby Cool store opened at the Bellavita Shopping Center, a high-end department store in Taiwan, followed by another one in the French department store Printemps in 2018. It began to expand into overseas markets including Hong Kong and China in 2019.However, after the COVID-19 outbreak in 2020, Baby Baby Cool shifted its focus back home and started to make efforts toward an e-commerce platform, reaching out to potential customers via multiple channels. After it was introduced to Sparklabs Taiwan, a Taiwan Tech Arena (TTA) accelerator partner, it received guidance that significantly helped it improve operation efficiency and rethink its management and marketing strategies.According to Wei, when Baby Baby Cool was first founded, a decision was made to tackle the most difficult sales channel. It took a while to get in touch with Bellavita but Baby Baby Cool was able to prove that their product quality is on par with hundred-year-old brands'.From the first presentation to the final product introduction conducted in a way similar to museum exhibits, Baby Baby Cool successfully convinced Bellavita to carry its brand. This helped considerably in Baby Baby Cool's subsequent business development.The startup faced the same challenge in 2023 again when it engaged in talks with Japan's Hankyu Department Store and Isetan Department Store. Wei was happy to win recognition from the two Japanese department stores. The availability of Baby Baby Cool clothes at their stores starting second-quarter 2024 will allow more visibility on Taiwan-based brands.Undertaking all-out efforts toward overseas market expansion starting this year, aside from Japan, Baby Baby Cool will shift focus back to France again in 2025. As part of the efforts, it will more actively participate in TTA's events in hopes of leveraging TTA's global visibility and network to find more partners and investors that will enable Taiwan-based brands to keep shining on the global stage.(Editor's note: The original article was published in TTA Magazine Issue 14. Read more startup stories in TTA Magazines.)Baby Baby Cool founder and director Erin Wei

Passive infrared (PIR) sensors have been around for years and are widely used in various devices including smart lamps, automotive radar, and monitoring systems.They are instrumental and indispensable to the modern world. However, their lower sensitivity and smaller range also limit the capability of the smart devices that use PIR sensors.Millimeter wave (mmWave) radar sensors that are widely used in smart cars are now getting increasingly adopted in smart devices including monitoring and smart cockpit systems after manufacturers started to provide non-automotive mmWave radar chips a few years ago at more economical pricing. Millilab, with a robust R&D capability and technological strength, wowed visitors at CES 2023. It has engaged in close partnerships with multiple international monitoring system suppliers. Having raised NT$50 million in March 2024, Millilab is poised to capture the immense opportunities in the global smart vehicle market.According to Millilab's founder and CEO - Bibben Lin, mmWaves are shorter in wavelengths. Sensors based on mmWave radar technology provide higher resolution and accuracy so they are embraced by smart cars with high safety standards.Infineon used to dominate the mmWave radar chip market, making them expensive and hardly used in monitoring systems sold at lower prices compared to smart cars. When Texas Instruments (TI) introduced low-cost mmWave radar chips, it spurred a rapid increase in mmWave radar sensor adoptions in non-automotive applications. Today, almost all mid-range and high-end monitoring systems priced at US$200 or higher use mmWave radar sensors.Recognized by Japan-based Socionext, Millilab targets the global market with technological strengthEyeing mmWave radar sensors' high accuracy and high-resolution characteristics and the opportunities arising from decreasing costs, Lin with abundant experience in developing communication devices decided to found Millilab with his business partners in 2019. Millilab's mmWave radar solutions are being used in monitoring systems for infants and seniors, child presence detection (CPD) systems, and driver monitoring systems (DMS).When the company was first founded, the Millilab team focused on developing algorithms based on TI mmWave radar sensors for a variety of applications. Millilab's robust R&D capability soon caught the attention of Socionext, a Japan-based mmWave radar chip supplier.Each boasting unique technologies in their own field, the two companies decided to join forces and have together developed total solutions and reference designs for a diversity of application scenarios that are embraced by customers across different sectors. Millilab has become one of the most trusted partners of Socionext and now independently develops algorithms based on Socionext chips. It is also the company that many global brands turn to for mmWave radar solutions.Lin noted that during the company's early development, the competition was fierce in the automotive mmWave radar sensor market. European and American brands dominated 80% to 90% of the market and the rest was divided between two China-based vendors.In comparison, at that time almost every monitoring system was based on the PIR technology. This presented tremendous opportunities for Millilab. Not only did Millilab become Socionext's partner for its R&D strength but it also secured a deal with Europe's largest car seat brand Maxi-Cosi to jointly develop a crib (baby) monitoring system. The result impressed Maxi-Cosi and more importantly, gave Millilab global visibility.Millilab and partners expand into the smart cockpit market with authorities mandating CPD starting 2025With the assistance from TTA and flyingVest Ventures, Millilab attended CES in 2023 and 2024 as well as London Tech Week in the U.K. and VivaTech in France. The participation at these events helped Millilab reach customers from different corners of the world.For example, a Europe-based automatic door manufacturer was impressed by Millilab's algorithm and therefore plans to collaborate with the company. Multiple Asia-based corporations have also engaged in partnerships with Millilab to provide mmWave radar solutions for their products targeting overseas markets. These projects significantly fueled Millilab's revenue growth.Going forward, Millilab will undertake a three-way strategy, said Lin. First, it will continue to attend tech exhibitions and work with TTA and flyingVest Ventures to increase its global visibility. Second, to win more customers across different sectors, Millilab plans to implement the algorithm developed for Socionext chips on TI chips, ensuring the same level of performance and reliability. Last, the EU mandating CPD starting in 2025 is set to spur the demand for CPD systems so Millilab will work with partners to capture preemptive opportunities in this market segment.On average, about 40 children die each year in Europe after being left alone in a car. To address this problem, Euro NCAP will award safety rating points for CPD in new passenger vehicle designs from 2025.In response, manufacturers are actively developing smart cockpit solutions. This presents a great opportunity for Millilab, boasting strong algorithm R&D capability, to penetrate the market segment. It plans to introduce a standard smart cockpit solution in April 2024 for automakers' PoC testing, followed by customized designs according to their requirements. Millilab expects this to contribute to strong revenue growth in the coming years.(Editor's note: The original article was published in TTA Magazine Issue 14. Read more startup stories in TTA Magazines.)Millilab founder and CEO Bibben LinPhoto: MillilabSchematic diagram of Millilab's CPD systemPhoto: Millilab

The global healthcare sector was amazed when a little girl with B-cell acute lymphoblastic leukemia was cured after being treated with chimeric antigen receptor (CAR) T-cell therapies (CAR-T) in 2012.Dr. Kuo-Hsiang Chuang, who just started his job at the Graduate Institute of Pharmacognosy, Taipei Medical University (TMU) at that time, thought CAR-T would help doctors and patients successfully fight cancer. However, CAR-T, mostly based on retrovirus gene delivery, leaves a lot of room for improvement. Dr. Chuang therefore developed the unique "Armed-T" technology and founded CytoArm in 2020, which now offers five T cell products against different cancers based on the Armed-T cell platform. CAR-T delivers effective results but has room for improvementAccording to a WHO report released on February 1, 2024, there were close to 20 million new cases of cancer in the year 2022 alongside 9.7 million deaths from cancer. It is not an exaggeration to call cancer the biggest threat to human health. This is also why the world including the healthcare sector is paying attention to CAR-T following the successful treatment of the little girl with leukemia in 2012.According to Dr. Chuang, CAR-T makes use of genetic engineering technologies to change the patient's immune cells called T cells, and enable them to effectively attack the cancer. T cells are collected from the patient and re-engineered in the laboratory to produce proteins on their surface called Chimeric Antigen Receptors (CAR) using retrovirus gene delivery.The genetically reengineered CAR-T cells can precisely identify tumor-specific antigens. When deployed back in the patient's body, CAR-T cells can specifically bind to cancer cells and destroy them.FDA approved the first CAR-T therapy in 2017, which has been proven to deliver promising results for blood cancers and impressive survival outcomes. However, Dr. Chuang pointed out the risks of CAR-T. First of all, it uses retrovirus vectors for gene delivery into T cells, which might elicit an unexpected immune response or cause T cell mutation.Furthermore, CAR-T costs will remain high as the processes of collecting, reengineering, and readministering T cells require a highly specialized team of professionals and expensive lab equipment. The gene (or virus) reengineering and cell culturing processes are also very challenging. Last but not least, CAR-T patents are owned by a small group of big pharma players, barring the entry of newcomers with formidable licensing fees or potential infringement lawsuits.Armed-T fights cancer even more effectivelyCytoArm's Armed-T technology addresses all of the above issues. According to Dr. Chuang, with Armed-T therapy, specific molecules are attached to the surface of the patient's T cell, much like putting armor on the T cell like Iron Man, described by Dr. Chuang.The armed T cells are then equipped to identify and destroy cancer cells. As opposed to CAR-T therapies that need 30 days for virus culture or reengineering, it only takes 10 days to produce high-purity cancer-fighting Armed-T cells and the therapeutic results are significantly more promising. To top it off, as no retrovirus gene delivery or genome editing technique is used, Armed-T cells are free of cancerization or mutation risks, making Armed-T a safer treatment choice for patients.In general, it is not easy for genetic reengineering techniques to achieve a high purity. CytoArm's Armed-T technology generates cancer-fighting cells at an impressive 90%+ purity. As to costs, without the need for retrovirus gene delivery, CytoArm can offer Armed-T technology at more affordable prices, allowing more patients to receive the treatment.Armed-T technology has another advantage, noted Dr. Chuang. The molecules that are attached to the surface of the T cell can be customized to allow the T cell to target and kill a specific type of cancer cell.CytoArm has developed five Armed-T products — CTA-01, CTA-02, CTA-03, CTA-04 and CTA-06. Experiments on lab mice with human B-cell leukemia indicate that CTA-01 can rapidly target and effectively destroy B-cell leukemia cancer cells with no obvious signs of recurrence. CTA-03 is for treating prostate cancer and CTA-04 is for treating metastatic breast carcinoma.CytoArm's first Armed-T product, CTA-02, is for treating incurable colorectal cancer associated with mutations in the epidermal growth factor receptor (EGFR) gene or its downstream effectors. In the first half of 2024, CytoArm is set to submit applications for CTA-02 clinical trials in Taiwan, Singapore, and the US.Poised to become a powerful weapon against cancer, CytoArm's Armed-T technology received worldwide attention following its introduction. Dr. Chuang named Taiwan's maturing startup ecosystem a key contributor to CytoArm's success.As a TMU-incubated startup, CytoArm developed a patent plan with TMU's guidance right when it was first founded. It also reached out to a U.S. IP firm for advice and confirmation that Armed-T does not infringe upon big pharma players' CAR-T patents, allowing the company to steer clear of obstacles that might hinder its research.The industry, government, and academia are stepping up efforts to support innovations and startups. Since CytoArm's establishment in 2020, capital investment, professional guidance, and market-driven strategies have all fueled the company's growth. Going forward, Dr. Chuang suggests that the government strengthen research grant and talent incubation policies and drive the commercialization of academic research to keep Taiwan's industry reinvigorated.CytoArm's Armed-T products. The first product, CTA-02, is for treating incurable colorectal cancer associated with mutations in the EGFR gene or its downstream effectors. Phase I clinical trials are scheduled to begin in 2024. It can be used to treat pancreatic cancer, lung cancer, TNBC and other types of cancer in the future.

The advent of burgeoning public cloud services has not only revolutionized personal digital experiences but has also significantly enhanced operational efficiencies and reduced management costs for corporations worldwide.Traditionally, retail and food franchises faced substantial expenditures on diverse devices and IT infrastructure optimization to oversee branch operations and devise unified marketing strategies. This often entailed establishing a central management platform in home office data centers, necessitating costly periodic visits by IT engineers—an expense beyond the means of many small and medium-scale retail chains.Founder and CEO of Kabob Cloud, Steve Tsai, emphasizes the proliferation of digital signage, kiosks, and smart devices over the past decade. An increasing number of retailers are leveraging these tools to streamline branch operations and minimize management expenses.Today, retail and food franchises can install Android TVs at their branch stores, enabling managers to oversee operations and gather data via public cloud platforms, thereby obviating the need for costly traditional systems. This innovation not only slashes management costs but also empowers franchise operators to swiftly adapt to market changes through diverse marketing campaigns, facilitating the growth of small and medium-scale franchises.Having established a robust presence in Taiwan, Kabob Cloud has successfully expanded its operations into Asia and North America. Anticipating the trend towards smaller displays and the rising popularity of Android TVs equipped with versatile apps, Kabob Cloud, founded in 2016, developed a suite of management tools tailored for food chains and retail brands. With enthusiastic reception in Asian markets, including China, Japan, and Singapore, Kabob Cloud has recently established branch offices in North America, and partnered with distributors in Korea and Australia to further expand its footprint.To cater to evolving market demands, Kabob Cloud offers a comprehensive suite of 20 diverse service apps. They include digital signage management (Lookr), audio management (Voicer), advertisement integration (Adder), omnichannel content marketing (Fafa), queue management (Tico), staff training (Teachor), and floor guidance (Kiosk).Business owners can seamlessly deploy these service apps onto various devices at their stores via Kabob Cloud's platform, which boasts an intuitive management interface and hassle-free configuration. As a result, Kabob Cloud's solutions have garnered adoption by over 500 franchise brands, including industry giants such as McDonald's, SEPHORA, Burger King, MeetFresh, and Ganso, spanning over 110,000 connected devices across 30,000 stores.Tsai highlights that while Kabob Cloud initially targeted food and retail chains, its smart remote management and face recognition solutions are also suitable for AIoT applications. Consequently, these solutions find applications in diverse sectors, including manufacturing, real estate, and telecommunications. Kabob Cloud's participation in CES 2023 proved instrumental in bolstering its presence in North American markets, attracting significant attention from industry professionals and generating numerous inquiries.With subscription-based services becoming increasingly prevalent, Kabob Cloud recognizes the proliferation of similar offerings in the market. However, unlike many solution providers offering bundled software and hardware packages, Kabob Cloud's solutions seamlessly operate across various devices and brands used at franchise stores, supporting multiple platforms such as Android, Linux, Windows, and iOS. This flexibility allows business owners to choose devices based on their preferences, budgets, and store characteristics, while managing and maintaining all devices effortlessly via a centralized platform, thereby maximizing operational efficiency.In response to intensifying market competition and evolving application scenarios, Kabob Cloud is committed to ongoing app development and collaboration with third-party software developers to expand its offerings. By establishing a software marketplace, Kabob Cloud aims to foster mutually beneficial partnerships with customers and partners, ensuring its continued leadership in the industry.(Editor's note: The original article was published in TTA Magazine Issue 14. Read more startup stories in TTA Magazines.)Kabob Cloud – a one-stop management platform integrating multiple applicationsPhoto: Kabob Cloud

As the global lingua franca, English communication skills are crucial for anyone looking to succeed in academics and the workplace.However, improving English proficiency typically requires a lot of effort for non-native speakers, especially in listening and speaking. Immersing in an all-English environment and having a 24/7 personal tutor who converses exclusively in English would be immensely beneficial for any learner, but not everyone can afford it, finding the right teacher is another challenge.This was also the challenge faced by Vu Van, who was born and raised in Vietnam. She initially thought her English level was good enough, and she got many opportunities in the local job market to work for international companies because of her language proficiency. It was not until Vu went to study at Stanford University, where she pursued an MBA and a Master's in Education that she realized her non-native accent prevented her from freely expressing herself and communicating smoothly with professors and classmates.The situation left her feeling frustrated so she started to look for a speech coach to improve her pronunciation. It turned out extremely expensive, the hourly rate could be as high as $200. All these became the driving force behind her founding ELSA eight years ago.Aimed to create an affordable personal English tutor available 24/7, Vu collaborated with a speech technologist, Dr. Xavier Anguera, to form a company and officially launched ELSA Speak in 2016. According to Michael Ngo, ELSA's General Manager of SEA Cluster and Taiwan, leveraging AI technologies and a self-built large database, the ELSA Speak smartphone app is not only a personal English tutor right in learners' pockets, but also a unique learning tool that can pinpoint pronunciation mistakes in every sound of a word and sentence, even at conversation level, then provide real-time, accurate feedback to guide users on how to improve.8 years ago, AI was not such a hot topic as today, "there were existing models that were available, but none of them were good enough for what we want," Ngo said. At the time, AI models could only conduct certain conversations but were unable to serve as learning tools. So the ELSA team built their own AI model and introduced generative AI technology to their solutions, to enable a unique personalized English learning tool."Recently, we've successfully developed & released two more powerful AI tools that bring users' English to the next level. One is ELSA AI, which lets users practice real-world roleplay conversations with AI and Speech Analyzer, which provides detailed feedback for any free-formed speeches." As Ngo mentioned, these tools are not only capable of engaging in ongoing conversations with users without limitation of time and location, help to correct pronunciation and grammar, but also simulate specific scenarios, such as job interviews and business conversations, allowing users to practice before entering the actual events, enhancing their confidence.ELSA's uniqueness and advantages have gained favor from numerous investors, including leading venture capital firms in Silicon Valley, Southeast Asia, and Japan. Gradient Ventures, an outstanding venture fund specializing in investing in the AI of Google is also one of them. So far ELSA has successfully raised $50 million in capital and got over 50 million downloads globally, their subscribers across more than 195 countries worldwide.Since its launch, ELSA has also won many prestigious awards and recognitions, including "Best Digital Learning App" by Reimagine Education, winner of SXSWEdu Launch Competition, the leading education technology exhibition in the US, Top 5 Artificial Intelligence Applications by Research Snipers, and a world-changing AI product mentioned by Forbes. Recently, ELSA has secured Series C funding, including the participation of UniPresident Taiwan. ELSA will use the funding "to support, grow the platform, and expand our global offering by increasing our presence further in Taiwan with our new investors," Vu said.With its semiconductor and electronics industry supply chain, Taiwan plays an increasingly significant role in the global market. More and more international companies have come for investment, increasing the need for local employees with bilingual skills. Taiwanese companies also need many experts with a variety of abilities, including English and international mobility, to adapt to global supply chain deployment. ELSA recognizes the growth potential of the Taiwan market and considers it one of the key focuses for future operations."And we see Taiwan has set a goal of becoming bilingual in Chinese and English by 2030. To achieve that goal, the Taiwanese government also urged educators and learners to leverage technology and AI for people to practice English with more effective, personalized, and engaging methodologies." Ngo added that, in addition to subscription service for individual users, collaborating with schools and businesses to provide English training solutions has always been one of the business models that ELSA values greatly.Ngo recalls how a blue-collar worker who worked in a factory in Vietnam improved his English proficiency significantly within six months with ELSA's tools and got the opportunity to study abroad. After completing his studies and returning to Vietnam, he obtained higher-level job opportunities and pay. ELSA has also helped a stay-at-home mother who relocated to the United States with her husband to master English language skills and the ability to run her small businesses to contribute to their households financially. These success stories motivate ELSA to continue improving and providing subscribers with a better user experience.As a successful startup, ELSA also shared its tips for operating a business with other entrepreneurs. " First, start with the big problem, because if the problem you try to solve is too small or too niche, you won't be able to scale up," Ngo said. Second, stay agile, "As technology advances rapidly, it's crucial to constantly assess the market's response to your products and services, swiftly determine the necessary changes and what's your next step." Last but not least, "Always focus on the end user's experience. Building a cool product is good, but if nobody uses it or has no value, it's probably not going to be a viable business."(Editor's note: The original article was published in TTA Magazine Issue 14. Read more startup stories in TTA Magazines.)ELSA English AI tutor

Electric vehicle (EV) makers exert every effort to resolve range anxiety by boosting the EV range by either increasing the battery output or decreasing the power consumption. As opposed to today's commonplace approaches of raising the battery capacity, Taiwan-based startup PurismEV has developed an AI-enabled adjustment system that improves the EV battery and motor efficiency based on driving habit analysis, thereby increasing the EV range by more than 40%. The system provides a quick solution for automakers, ride-sharing fleets, and logistics companies with a limited budget to optimize their operating costs.According to PurismEV COO Ming-hsuan Chu, raising the battery capacity may increase the EV range but it also adds to the vehicle's cost and weight. A smarter approach is to both increase the battery energy efficiency and decrease the power consumption. PurismEV's solution performs automated EV system calibrations based on driving habits and throttle control to thereby significantly boost the EV range with no need for larger battery capacity.As a seasoned veteran in the motorcycle industry, Chu started her career in the motorcycle component import/export business, searching for suitable Taiwan-made products for foreign motorcycle manufacturers. She discovered the enormous development potential of EV components after receiving a big order. This motivated her to found PurismEV with Gigi Huang, who has abundant experience in EV batteries. Joining forces, they endeavor to develop solutions that enhance EV energy efficiency while taking costs into consideration.In charge of the startup's product R&D, Huang designed PurismEV's AI energy efficiency solution to comprise two elements – an in-vehicle system and a cloud-based platform. The in-vehicle system collects the throttle and the driver's behavior data and adjusts the throttle responses according to machine learning algorithms. The collected data is forwarded to PurismEV's cloud platform with built-in digital twin models with the following features: 1) AI-based battery and motor degradation prediction, 2) battery safety and health prediction, and 3) driving habits analytics and creation of optimized control instructions. All these data mentioned above are then sent back to the in-vehicle system to perform optimized vehicle control, thereby boosting efficiency and safety. Compared to conventional fleet management systems, PurismEV's solution delivers more on-target and effective energy efficiency enhancements. Conventional fleet management systems have the in-vehicle computer log the data collected from the throttle and brake sensors which is downloaded from the vehicle after it returns to the base. The data is then analyzed and based on the results, drivers are assisted automatically to develop better driving habits, which is thanks to the unique dynamic calibrations done by PurismEV. There are two EV throttle control modes generally used by vehicle OEMs: Eco mode with power limitation and fixed throttle response curve, both of which could only deliver between 17% to 19% reduction in power consumption.PurismEV's solution dynamically adjusts the throttle curve based on software calculations of motor operating conditions detected by the sensor. The dynamic calibrations taking into account real-time data of the driving scenario, driver behavior and motor condition enable the motor to output a constant torque. Field test results indicate PurismEV's solution achieves over 40% energy savings. Moreover, automated calibrations are performed by the system with no driver interference, which ensures the energy efficiency enhancement is actually delivered without failure.Apart from the energy efficiency enhancement, PurismEV's product development process is another noteworthy feat. Both co-founders are seasoned veterans in the motor vehicle business. Huang, in charge of system R&D, drew on his practical experiences and leveraged Taiwan's complete supply chain resources to develop PurismEV's solution in just ten months, from design to commercialization. PurismEV has also secured a stable component supply. With ready access to components on the market, PurismEV has full control of the costs and volume production process.PurismEV operates two business models. The in-vehicle system is provided on a one-time sale basis while the cloud service is offered on an annual subscription basis. Its target customers include ride-sharing service operators and logistics companies with their own fleets. Its solution has been adopted by a major motorcycle ride-sharing service provider in Taiwan for trial purposes, proven to deliver over 40% energy savings as promised. As part of its efforts to expand globally, PurismEV has made itself seen on multiple occasions in markets abroad and is actively engaging with European and American customers to broaden its reach. With the commercialization underway, PurismEV's solution was recently showcased at trade exhibitions in Italy and the U.S., gaining market visibility. Chu noted that Taiwan-based startups are expanding their presence in the worldwide market thanks to a friendlier environment fostered by government support policies and private-sector investments. The types and quantity of investors are both rapidly growing, giving rise to more opportunities for startups to get funded. Chu hopes for prosperity to continue and invigorate Taiwan's industry, thereby creating a win-win situation for the business sector and the community.Product system diagramPhoto: PurismEVPurismEV throttle controlPhoto: PurismEV